Prevention of feeling or being sick Give 1st dose 1 hr before radio- or chemotherapy. 1 or 2 mg once daily for up to a wk after radio- or chemotherapy. Treatment of feeling or being sick 1 or 2 mg once daily; may be increased up to nine 1 mg tab a day.
Problems w/ bowel movements; heart problems; concomitant use w/ a medicine that is known to damage the heart; electrolyte abnormalities; concomitant use w/ other serotonin receptor antagonist. Life-threatening serotonin syndrome.
Medicines used to treat an irregular heartbeat, other serotonin receptor antagonist (eg, dolasetron or ondansetron), phenobarb, ketoconazole, erythromycin.
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